PSMC1P5

Across TCGA pan-cancer cohorts, PSMC1P5 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of PSMC1P5’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where PSMC1P5 RNA is repressed in tumor relative to normal tissue. In most cancer types PSMC1P5 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

COAD, STAD, and LUSC are the cancer types where PSMC1P5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PSMC1P5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	−0.177	.005	3	view →
STAD	Male	All	+0.337	.049	1	view →
LUSC	Male	All	+0.161	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

PSMC1P5–COAD

Open the COAD breakdown →