PSMB6

Across TCGA cell cohorts, PSMB6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,841 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PSMB6-associated GO terms across cancer lineages are Telomere assembly, Regulation of establishment of protein localization to telomere, and 5-phosphoribose 1-diphosphate metabolic process. Each is linked with PSMB6 in more than 13 cancer types. Because this analysis shows association rather than direction, both PSMB6-to-partner and partner-to-PSMB6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere assembly grouped by PSMB6-low versus PSMB6-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMB6→partner) and Y-score (partner→PSMB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Telomere assembly →	+0.160	+0.900	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of establishment of protein localization to telomere →	+0.111	+0.823	<.001	<.001	3	13
OVARY	5-phosphoribose 1-diphosphate metabolic process →	+0.131	+0.795	<.001	<.001	3	12
OVARY	5-phosphoribose 1-diphosphate biosynthetic process →	+0.131	+0.795	<.001	<.001	3	12
SKIN	rRNA methylation →	+0.058	+0.421	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Ribosomal small subunit export from nucleus →	+0.106	+0.859	.004	.005	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,841 associations by consensus.

Telomere assembly by PSMB6 expression — LUNG_SCLC

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