PSMB5

Across TCGA patient cohorts, PSMB5 protein abundance is significantly associated with the RNA expression of many other genes, with 12,752 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PSMB5-associated genes across cancer lineages are ETV7, BTN3A3, and IFIH1. Each is linked with PSMB5 in more than 9 cancer types. Because this analysis shows association rather than direction, both PSMB5-to-partner and partner-to-PSMB5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSMB5 versus ETV7 in HNSC, with a Pearson correlation of -0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMB5→partner) and Y-score (partner→PSMB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ETV7 →	-1.153	-0.450	<.001	<.001	3	10
HNSC	BTN3A3 →	-0.974	-0.526	<.001	<.001	3	10
OV	IFIH1 →	-1.066	-0.540	<.001	<.001	3	10
BRCA	IFIT3 →	-1.417	-0.426	<.001	<.001	3	10
BRCA	NMI →	-1.047	-0.491	<.001	<.001	3	10
BRCA	EPSTI1 →	-1.135	-0.564	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,752 associations by consensus.

PSMB5 vs ETV7 — HNSC

Explore this scatter interactively →