PSMB3

Across TCGA patient cohorts, PSMB3 protein abundance is significantly associated with the RNA expression of many other genes, with 6,691 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PSMB3-associated genes across cancer lineages are PSMB9, WARS1, and CD7. Each is linked with PSMB3 in more than 4 cancer types. Because this analysis shows association rather than direction, both PSMB3-to-partner and partner-to-PSMB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSMB3 versus PSMB9 in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMB3→partner) and Y-score (partner→PSMB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PSMB9 →	+1.338	+0.298	.001	<.001	3	5
LSCC	WARS1 →	+0.822	+0.136	<.001	.004	3	5
BRCA	CD7 →	+1.101	+0.222	<.001	<.001	3	5
BRCA	SH2D2A →	+0.965	+0.199	.001	.001	3	5
OV	HLA-B →	+1.301	+0.273	.002	.002	3	4
OV	ETV7 →	+1.184	+0.260	.003	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,691 associations by consensus.

PSMB3 vs PSMB9 — OV

Explore this scatter interactively →