PSMA7

Across TCGA cell cohorts, PSMA7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,730 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PSMA7-associated GO terms across cancer lineages are DNA replication initiation, Spliceosomal snRNP assembly, and Thymidine biosynthetic process. Each is linked with PSMA7 in more than 13 cancer types. Because this analysis shows association rather than direction, both PSMA7-to-partner and partner-to-PSMA7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by PSMA7-low versus PSMA7-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMA7→partner) and Y-score (partner→PSMA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA replication initiation →	+0.158	+0.512	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Spliceosomal snRNP assembly →	+0.099	+0.642	<.001	<.001	3	14
OESOPHAGUS	Thymidine biosynthetic process →	+0.197	+1.069	<.001	<.001	3	13
OESOPHAGUS	2'-deoxyribonucleoside biosynthetic process →	+0.197	+1.069	<.001	<.001	3	13
OESOPHAGUS	Pyrimidine deoxyribonucleoside biosynthetic process →	+0.197	+1.069	<.001	<.001	3	13
SKIN	Pyrimidine nucleoside monophosphate biosynthetic process →	+0.141	+0.825	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,730 associations by consensus.

DNA replication initiation by PSMA7 expression — BONE

Explore this box plot interactively →