PSMA6

Across TCGA patient cohorts, PSMA6 protein abundance is significantly associated with the RNA expression of many other genes, with 10,717 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PSMA6-associated genes across cancer lineages are TAP1, EDIL3, and GZMA. Each is linked with PSMA6 in more than 5 cancer types. Because this analysis shows association rather than direction, both PSMA6-to-partner and partner-to-PSMA6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSMA6 versus TAP1 in UCEC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMA6→partner) and Y-score (partner→PSMA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TAP1 →	+1.344	+0.208	<.001	<.001	3	6
BRCA	EDIL3 →	-1.191	-0.157	.002	.002	3	5
BRCA	GZMA →	+1.389	+0.237	<.001	<.001	3	5
UCEC	GFI1 →	+0.735	+0.157	.001	.004	3	5
BRCA	PDCD1 →	+1.290	+0.286	<.001	<.001	3	5
COAD	PSMB9 →	+1.102	+0.224	.001	.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,717 associations by consensus.

PSMA6 vs TAP1 — UCEC

Explore this scatter interactively →