PSMA4

Across TCGA patient cohorts, PSMA4 protein abundance is significantly associated with the RNA expression of many other genes, with 6,598 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PSMA4-associated genes across cancer lineages are STAT1, WARS1, and TPPP3. Each is linked with PSMA4 in more than 3 cancer types. Because this analysis shows association rather than direction, both PSMA4-to-partner and partner-to-PSMA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSMA4 versus STAT1 in BRCA, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMA4→partner) and Y-score (partner→PSMA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	STAT1 →	+1.105	+0.229	<.001	<.001	3	4
BRCA	WARS1 →	+0.885	+0.246	<.001	<.001	3	4
GBM	TPPP3 →	-1.131	-0.123	.001	.006	3	4
BRCA	GBP4 →	+1.186	+0.179	<.001	.002	3	4
UCEC	WFDC1 →	-0.643	-0.233	.004	<.001	3	3
UCEC	DNM1 →	-0.730	-0.189	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,598 associations by consensus.

PSMA4 vs STAT1 — BRCA

Explore this scatter interactively →