PSMA4

Across TCGA cell cohorts, PSMA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,213 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PSMA4-associated GO terms across cancer lineages are Protein localization to condensed chromosome, Spindle elongation, and Immunoglobulin heavy chain V-D-J recombination. Each is linked with PSMA4 in more than 17 cancer types. Because this analysis shows association rather than direction, both PSMA4-to-partner and partner-to-PSMA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to condensed chromosome grouped by PSMA4-low versus PSMA4-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMA4→partner) and Y-score (partner→PSMA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein localization to condensed chromosome →	+0.168	+0.705	<.001	.002	3	18
LUNG_NSCLC_LUSC	Spindle elongation →	+0.231	+0.914	.006	.004	2	17
BREAST	Immunoglobulin heavy chain V-D-J recombination →	+0.188	+0.765	<.001	.006	3	16
BREAST	Regulation of cell cycle checkpoint →	+0.127	+1.006	<.001	<.001	3	16
BREAST	Regulation of mitotic sister chromatid segregation →	+0.180	+1.025	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Protein localization to kinetochore →	+0.153	+0.929	.001	.001	2	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,213 associations by consensus.

Protein localization to condensed chromosome by PSMA4 expression — OESOPHAGUS

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