PSMA2

Across TCGA patient cohorts, PSMA2 protein abundance is significantly associated with the RNA expression of many other genes, with 406 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PSMA2-associated genes across cancer lineages are SPECC1L, SNRPD3, and HPS4. Each is linked with PSMA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMA2-to-partner and partner-to-PSMA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSMA2 versus SPECC1L in GBM, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMA2→partner) and Y-score (partner→PSMA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SPECC1L →	-0.368	-0.658	.008	.009	3	1
GBM	SNRPD3 →	-0.530	-0.901	.005	<.001	3	1
GBM	HPS4 →	-0.549	-0.802	<.001	.001	3	1
GBM	SRRD →	-0.506	-0.715	<.001	.004	3	1
GBM	PATZ1 →	-0.591	-0.736	.005	<.001	3	1
GBM	PNPLA5 →	+0.434	+0.840	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 406 associations by consensus.

PSMA2 vs SPECC1L — GBM

Explore this scatter interactively →