PSMA2

Across TCGA cell cohorts, PSMA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,475 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PSMA2-associated GO terms across cancer lineages are Metaphase chromosome alignment, Protein localization to chromosome, centromeric region, and Centromeric sister chromatid cohesion. Each is linked with PSMA2 in more than 12 cancer types. Because this analysis shows association rather than direction, both PSMA2-to-partner and partner-to-PSMA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Metaphase chromosome alignment grouped by PSMA2-low versus PSMA2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMA2→partner) and Y-score (partner→PSMA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Metaphase chromosome alignment →	+0.089	+0.773	.006	.002	3	13
OESOPHAGUS	Protein localization to chromosome, centromeric region →	+0.135	+0.831	<.001	<.001	3	12
OESOPHAGUS	Centromeric sister chromatid cohesion →	+0.168	+1.187	.004	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.156	+0.927	<.001	<.001	3	12
OESOPHAGUS	Protein localization to kinetochore →	+0.150	+0.819	<.001	<.001	3	12
OESOPHAGUS	Regulation of mitotic sister chromatid separation →	+0.143	+0.759	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,475 associations by consensus.

Metaphase chromosome alignment by PSMA2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →