PSG8

Across TCGA cell cohorts, PSG8 RNA expression is significantly associated with the go_rna of many other GO terms, with 858 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PSG8-associated GO terms across cancer lineages are Cellular response to folic acid, Regulation of protein ubiquitination, and Golgi to plasma membrane protein transport. Each is linked with PSG8 in more than 5 cancer types. Because this analysis shows association rather than direction, both PSG8-to-partner and partner-to-PSG8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to folic acid grouped by PSG8-low versus PSG8-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSG8→partner) and Y-score (partner→PSG8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cellular response to folic acid →	+0.686	+0.040	.005	.008	3	5
UPPER_AERODIGESTIVE_TRACT	Regulation of protein ubiquitination →	+0.033	+0.498	.003	.002	3	5
UPPER_AERODIGESTIVE_TRACT	Golgi to plasma membrane protein transport →	+0.080	+0.595	.001	.006	3	5
LUNG_NSCLC_LUAD	Regulation of response to endoplasmic reticulum stress →	+0.049	+0.860	<.001	.006	2	6
LUNG_NSCLC_LUAD	Vacuolar transport →	+0.034	+1.148	<.001	.004	3	5
LUNG_NSCLC_LUAD	Endosome to lysosome transport →	+0.034	+0.763	.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 858 associations by consensus.

Cellular response to folic acid by PSG8 expression — BONE

Explore this box plot interactively →