PSG2

Across TCGA cell cohorts, PSG2 mutation is significantly associated with the mutation status of many other genes, with 1,025 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PSG2-associated genes across cancer lineages are KCNH7, CPXCR1, and CCDC13. Each is linked with PSG2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PSG2-to-partner and partner-to-PSG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCNH7 grouped by PSG2-low versus PSG2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSG2→partner) and Y-score (partner→PSG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KCNH7 →	+2.729	+3.643	<.001	<.001	1	3
SKIN	CPXCR1 →	+4.392	+4.392	.009	.009	1	3
SKIN	CCDC13 →	+4.392	+4.392	.009	.009	1	2
LARGE_INTESTINE	FOLH1 →	+1.836	+2.906	.009	.009	1	2
LARGE_INTESTINE	PTPN4 →	+2.407	+2.886	.008	.008	1	2
LARGE_INTESTINE	IL5RA →	+2.630	+3.047	.005	.005	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,025 associations by consensus.

KCNH7 by PSG2 expression — LARGE_INTESTINE

Explore this box plot interactively →