PSG10P

Across TCGA patient cohorts, PSG10P mutation is significantly associated with the RNA expression of many other genes, with 5,612 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSG10P-associated genes across cancer lineages are SLC25A5P9, CCNB1IP1, and TMEM87A. Each is linked with PSG10P in more than 2 cancer types. Because this analysis shows association rather than direction, both PSG10P-to-partner and partner-to-PSG10P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC25A5P9 grouped by PSG10P-low versus PSG10P-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSG10P→partner) and Y-score (partner→PSG10P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SLC25A5P9 →	+0.048	+5.288	<.001	.006	3	3
UCEC	CCNB1IP1 →	+0.581	+3.332	.001	.005	3	3
SKCM	TMEM87A →	+0.610	+2.241	<.001	<.001	3	3
SKCM	PMPCB →	+0.518	+2.241	<.001	<.001	3	3
UCEC	RIC8B →	+0.482	+4.108	<.001	<.001	3	3
UCEC	UBE3A →	+0.612	+3.000	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,612 associations by consensus.

SLC25A5P9 by PSG10P expression — BRCA

Explore this box plot interactively →