PSD4

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PSD4 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,107 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PSD4-associated proteins across cancer lineages are MDC1, CBX2, and ABCF1. Each is linked with PSD4 in more than 3 cancer types. Because this analysis shows association rather than direction, both PSD4-to-partner and partner-to-PSD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSD4 versus MDC1 in LSCC, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PSD4→partner) and Y-score (partner→PSD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCMDC1 →-0.348-0.544.002<.00134
GBMCBX2 →-0.948-0.771<.001<.00134
LSCCABCF1 →-0.224-0.371.006.00634
LSCCFLII →+0.196+0.331<.001.00234
OVPRAM1_S484 →+0.604+0.611.002.00133
BRCAMARCKSL1_S104 →-1.137-0.687.002.00233
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,107 associations by consensus.

PSD4 vs MDC1 — LSCC

Per-sample scatter of PSD4 vs MDC1 in LSCC (Pearson r = -0.41).

Explore this scatter interactively →

Exploration