PSD4

Across TCGA cell cohorts, PSD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,800 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PSD4-associated GO terms across cancer lineages are Protein localization to plasma membrane, T cell mediated cytotoxicity, and Late endosome to lysosome transport. Each is linked with PSD4 in more than 11 cancer types. Because this analysis shows association rather than direction, both PSD4-to-partner and partner-to-PSD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to plasma membrane grouped by PSD4-low versus PSD4-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSD4→partner) and Y-score (partner→PSD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Protein localization to plasma membrane →	+0.065	+1.164	<.001	<.001	3	12
LUNG_NSCLC_LUAD	T cell mediated cytotoxicity →	+0.236	+1.474	<.001	<.001	3	11
STOMACH	Late endosome to lysosome transport →	+0.132	+1.563	<.001	<.001	3	11
LARGE_INTESTINE	Negative regulation of protein-containing complex assembly →	+0.072	+1.585	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Negative regulation of actin filament polymerization →	+0.135	+1.802	.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.100	-0.702	.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,800 associations by consensus.

Protein localization to plasma membrane by PSD4 expression — SKIN

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