PSD2-AS1

Across TCGA pan-cancer cohorts, PSD2-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated PSD2-AS1 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher PSD2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PSD2-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRP show a favorable association.

COAD, THCA, and READ are the cancer types where PSD2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	II,III,IV	0.470	0.706	<.001	45	view →
THCA	OS	Tertile	IV	0.551	0.924	.007	42	view →
READ	DFS	Tertile	II,III,IV	0.442	0.749	<.001	33	view →
UCS	DFS	Tertile	II,III,IV	0.147	0.529	.005	30	view →
LGG	OS	Median	All	0.855	0.931	<.001	28	view →
CHOL	DFS	Tertile	II,III,IV	0.146	0.539	.028	18	view →
LUAD	OS	Tertile	IV	0.262	0.618	.045	18	view →
LIHC	OS	Tertile	III,IV	0.092	0.615	<.001	18	view →
ESCA	OS	Tertile	All	0.510	1.000	.006	12	view →
CESC	DFS	Tertile	III,IV	0.166	0.475	.022	12	view →
LUSC	DFS	Quartile	III,IV	0.141	0.759	.002	12	view →
UCEC	DFS	Tertile	II,III,IV	0.746	0.842	.022	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

PSD2-AS1–COAD (DFS)

Open the COAD breakdown →