PSD2-AS1

Across TCGA pan-cancer cohorts, PSD2-AS1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of PSD2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where PSD2-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PSD2-AS1 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.

COAD, BRCA, and STAD are the cancer types where PSD2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PSD2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.132	.001	4	view →
BRCA	Female	All	+0.120	.013	4	view →
STAD	All	All	+0.105	.005	3	view →
ESCA	All	II,III,IV	+0.375	.020	2	view →
LUSC	All	All	+0.106	.009	2	view →
KIRP	Male	All	−0.071	.020	2	view →
THCA	All	All	+0.061	.007	2	view →
KIRC	All	All	+0.054	.012	2	view →
CHOL	All	All	+0.222	.028	1	view →
LUAD	All	All	+0.134	.013	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

PSD2-AS1–COAD

Open the COAD breakdown →