Across TCGA pan-cancer cohorts, PRYP1 RNA is linked to patient survival in 2 of 34 cancer types, making it the most broadly survival-associated PRYP1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PRYP1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PRYP1 expression acts as an unfavorable survival marker.

HNSC and ESCA are the cancer types where PRYP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.163	0.696	.007	72	view →
ESCA	OS	Tertile	All	0.211	0.876	.028	18	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: PRYP1 tumor-vs-normal RNA expression · all PRYP1 data types