PRYP1

Q-omics provides the consensus-scored PRYP1 profile across patient tissues and cancer cell-line models. PRYP1 expression is associated with patient survival in 2 of 34 cancer types, with the highest sampling consensus in HNSC. Additionally, PRYP1 RNA expression shows 771 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight HNSC, and STAD as cancer lineages where PRYP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes PRYP1 survival associations across molecular data types. PRYP1 RNA expression shows survival associations in the most cancer types (2). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

PRYP1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	2	HNSC (72)	view →

This table ranks reproducible PRYP1 RNA expression–survival associations across cancer types. High PRYP1 expression shows unfavorable associations in HNSC and ESCA. The HNSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .007). Together, the overview and detailed table identify HNSC as the clearest survival context for PRYP1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.163	0.696	.007	72	view →
ESCA	OS	Tertile	All	0.211	0.876	.028	18	view →

Pink = unfavorable, green = favorable. all 2 lineages →

PRYP1-HNSC (DFS)

Explore this curve interactively →