PRXL2B

Across TCGA patient cohorts, PRXL2B protein abundance is significantly associated with the RNA expression of many other genes, with 14,783 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PRXL2B-associated genes across cancer lineages are MMEL1, TNFRSF14-AS1, and GIPR. Each is linked with PRXL2B in more than 6 cancer types. Because this analysis shows association rather than direction, both PRXL2B-to-partner and partner-to-PRXL2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRXL2B versus MMEL1 in UCEC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRXL2B→partner) and Y-score (partner→PRXL2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MMEL1 →	+0.782	+0.495	<.001	<.001	3	7
PDAC	TNFRSF14-AS1 →	+0.631	+0.406	<.001	.001	3	6
BRCA	GIPR →	+1.142	+0.339	<.001	<.001	3	5
UCEC	TTLL9 →	+1.194	+0.330	<.001	<.001	3	5
BRCA	AQP7 →	+0.840	+0.216	<.001	.005	3	5
BRCA	BCAS1 →	+2.384	+0.421	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,783 associations by consensus.

PRXL2B vs MMEL1 — UCEC

Explore this scatter interactively →