PRXL2A

Across TCGA patient cohorts, PRXL2A protein abundance is significantly associated with the RNA expression of many other genes, with 14,348 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRXL2A-associated genes across cancer lineages are TSPAN14, FKBP11, and SLC43A3. Each is linked with PRXL2A in more than 3 cancer types. Because this analysis shows association rather than direction, both PRXL2A-to-partner and partner-to-PRXL2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRXL2A versus TSPAN14 in LSCC, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRXL2A→partner) and Y-score (partner→PRXL2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TSPAN14 →	+0.457	+0.665	<.001	<.001	3	4
CCRCC	FKBP11 →	-0.411	-0.324	<.001	.001	3	4
UCEC	SLC43A3 →	-0.729	-0.568	.001	<.001	3	4
COAD	CTSL →	-0.848	-0.426	.001	.001	3	4
GBM	ADAM8 →	-0.858	-0.374	<.001	<.001	3	4
UCEC	HSP90B1 →	-0.623	-0.555	.004	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,348 associations by consensus.

PRXL2A vs TSPAN14 — LSCC

Explore this scatter interactively →