PRXL2A

Across TCGA cell cohorts, PRXL2A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,078 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PRXL2A-associated GO terms across cancer lineages are Dopamine transport, Catecholamine transport, and Cholesterol biosynthetic process via desmosterol. Each is linked with PRXL2A in more than 11 cancer types. Because this analysis shows association rather than direction, both PRXL2A-to-partner and partner-to-PRXL2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dopamine transport grouped by PRXL2A-low versus PRXL2A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRXL2A→partner) and Y-score (partner→PRXL2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Dopamine transport →	+1.690	+2.772	<.001	<.001	3	12
BONE	Catecholamine transport →	+1.589	+3.124	<.001	<.001	3	11
BREAST	Cholesterol biosynthetic process via desmosterol →	+0.196	+2.436	<.001	<.001	3	11
BREAST	Zymosterol metabolic process →	+0.199	+2.711	<.001	<.001	3	11
BREAST	Zymosterol biosynthetic process →	+0.199	+2.711	<.001	<.001	3	11
BREAST	Secondary alcohol metabolic process →	+0.142	+2.252	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,078 associations by consensus.

Dopamine transport by PRXL2A expression — BONE

Explore this box plot interactively →