PRTG

Across TCGA patient cohorts, PRTG RNA expression is significantly associated with the protein abundance of many other proteins, with 15,341 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRTG-associated proteins across cancer lineages are HDGFL3, PHLDB1, and SORBS3. Each is linked with PRTG in more than 7 cancer types. Because this analysis shows association rather than direction, both PRTG-to-partner and partner-to-PRTG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRTG versus HDGFL3 in HNSC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRTG→partner) and Y-score (partner→PRTG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HDGFL3 →	+0.709	+0.657	<.001	<.001	3	8
LSCC	PHLDB1 →	+0.594	+0.863	<.001	<.001	3	7
UCEC	SORBS3 →	+0.415	+0.808	.002	.003	3	7
PDAC	EFEMP2 →	+0.617	+0.456	<.001	<.001	3	6
UCEC	TGFB1I1 →	+0.622	+0.629	<.001	.008	3	6
UCEC	RSU1 →	+0.421	+0.757	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,341 associations by consensus.

PRTG vs HDGFL3 — HNSC

Explore this scatter interactively →