PRTG

Across TCGA pan-cancer cohorts, PRTG RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated PRTG data layer compared with 9 for mutation status.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher PRTG RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PRTG expression acts as an unfavorable survival marker, although some lineages such as HNSC and LGG show a favorable association.

STAD, ACC, and UVM are the cancer types where PRTG RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	All	0.493	0.670	<.001	129	view →
ACC	DFS	Median	All	0.267	0.636	<.001	77	view →
UVM	OS	Quartile	III,IV	0.275	0.915	.002	51	view →
COAD	DFS	Quartile	All	0.415	0.638	.001	50	view →
KICH	OS	Median	II,III,IV	0.455	1.000	<.001	43	view →
HNSC	DFS	Quartile	IV	0.668	0.438	.004	41	view →
LGG	DFS	Median	All	0.797	0.677	<.001	29	view →
BRCA	DFS	Tertile	III,IV	0.944	0.798	.002	25	view →
UCEC	OS	Tertile	II,III,IV	0.695	0.837	.014	24	view →
SKCM	OS	Median	III,IV	0.744	0.935	.002	23	view →
KIRP	DFS	Quartile	All	0.532	0.751	.011	22	view →
GBM	OS	Tertile	All	0.569	0.295	.009	22	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

PRTG–STAD (OS)

Open the STAD breakdown →