PRTG

Across TCGA cell cohorts, PRTG RNA expression is significantly associated with the go_rna of many other GO terms, with 4,629 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PRTG-associated GO terms across cancer lineages are NMDA glutamate receptor clustering, Renal vesicle formation, and Metanephric renal vesicle formation. Each is linked with PRTG in more than 7 cancer types. Because this analysis shows association rather than direction, both PRTG-to-partner and partner-to-PRTG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NMDA glutamate receptor clustering grouped by PRTG-low versus PRTG-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRTG→partner) and Y-score (partner→PRTG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	NMDA glutamate receptor clustering →	+1.329	+1.663	<.001	<.001	3	8
STOMACH	Renal vesicle formation →	+1.121	+1.220	<.001	<.001	3	8
STOMACH	Metanephric renal vesicle formation →	+1.121	+1.220	<.001	<.001	3	8
URINARY_TRACT	Ephrin receptor signaling pathway →	-0.161	-1.921	<.001	<.001	3	8
OESOPHAGUS	Cardiac conduction →	-0.159	-1.043	<.001	<.001	3	8
LARGE_INTESTINE	Potassium ion transmembrane transport →	-0.036	-0.739	<.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,629 associations by consensus.

NMDA glutamate receptor clustering by PRTG expression — SKIN

Explore this box plot interactively →