Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, PRSS57 mutation is significantly associated with the RNA expression of many other genes, with 324 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible PRSS57-associated genes across cancer lineages are RAB9BP1, SDHDP4, and ENSAP3. Each is linked with PRSS57 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRSS57-to-partner and partner-to-PRSS57 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (PRSS57→partner) and Y-score (partner→PRSS57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.