PRSS55

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PRSS55 RNA expression is significantly associated with the go_rna of many other GO terms, with 546 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible PRSS55-associated GO terms across cancer lineages are Regulation of autophagy of mitochondrion, Progesterone biosynthetic process, and Response to oxygen levels. Each is linked with PRSS55 in more than 3 cancer types. Because this analysis shows association rather than direction, both PRSS55-to-partner and partner-to-PRSS55 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS55→partner) and Y-score (partner→PRSS55) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADRegulation of autophagy of mitochondrion →+0.059+0.016.004.00933
LUNG_NSCLC_LUADProgesterone biosynthetic process →-0.131-0.011<.001.00533
OVARYResponse to oxygen levels →+0.045+0.010.001<.00133
OVARYMaintenance of protein localization in organelle →+0.066+0.010.007<.00133
PANCREASSterol transport →+0.060+0.028<.001.00233
PANCREASNegative regulation of lymphocyte mediated immunity →+0.100+0.030.004.00933
Each partner links to its Q-omics profile. Showing the 6 strongest of 546 associations by consensus.

Exploration