PRSS51

Across TCGA cell cohorts, PRSS51 RNA expression is significantly associated with the go_rna of many other GO terms, with 868 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRSS51-associated GO terms across cancer lineages are Response to starvation, Late endosome to vacuole transport via multivesicular body sorting pathway, and Positive regulation of protein transport. Each is linked with PRSS51 in more than 4 cancer types. Because this analysis shows association rather than direction, both PRSS51-to-partner and partner-to-PRSS51 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to starvation grouped by PRSS51-low versus PRSS51-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS51→partner) and Y-score (partner→PRSS51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Response to starvation →	+0.057	+0.935	<.001	.006	3	5
LUNG_NSCLC_LUAD	Late endosome to vacuole transport via multivesicular body sorting pathway →	+0.047	+0.375	.001	.009	2	5
BREAST	Positive regulation of protein transport →	+0.054	+0.448	<.001	.009	3	4
OVARY	Regulation of TOR signaling →	+0.042	+0.348	<.001	<.001	3	4
KIDNEY	Endosome organization →	+0.059	+0.111	.002	.008	2	5
BLOOD_Lymphoma	Regulation of type I interferon production →	+0.044	+0.628	<.001	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 868 associations by consensus.

Response to starvation by PRSS51 expression — BLOOD_Lymphoma

Explore this box plot interactively →