Across TCGA patient cohorts, PRSS45P mutation is significantly associated with the RNA expression of many other genes, with 103 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRSS45P-associated genes across cancer lineages are NDUFB4P9, RNU6-280P, and MIR626. Each is linked with PRSS45P in more than 1 cancer types. Because this analysis shows association rather than direction, both PRSS45P-to-partner and partner-to-PRSS45P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS45P→partner) and Y-score (partner→PRSS45P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	NDUFB4P9 →	+0.087	+4.970	<.001	.005	3	2
UCEC	RNU6-280P →	+0.235	+4.437	<.001	.005	3	2
SKCM	MIR626 →	+0.487	+4.970	<.001	.005	3	2
SKCM	RPPH1-3P →	+0.232	+6.219	<.001	<.001	3	2
UCEC	MIR6769A →	+0.862	+3.348	<.001	.001	3	1
UCEC	RN7SL769P →	+0.325	+2.847	.007	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 103 associations by consensus.

Exploration

PRSS45P survival (RNA) · tumor vs normal (RNA) · all PRSS45P data types