Across TCGA patient cohorts, PRSS45P mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRSS45P-associated genes across cancer lineages are VHL, Tuberin, and EGFR. Each is linked with PRSS45P in more than 1 cancer types. Because this analysis shows association rather than direction, both PRSS45P-to-partner and partner-to-PRSS45P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS45P→partner) and Y-score (partner→PRSS45P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	VHL →	-1.004	-3.000	.010	.036	3	1
UCEC	Tuberin →	+0.389	+2.817	.012	.036	2	1
UCEC	EGFR →	-0.194	-3.000	.035	.037	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

PRSS45P survival (RNA) · tumor vs normal (RNA) · all PRSS45P data types