PRSS42P

Across TCGA cell cohorts, PRSS42P RNA expression is significantly associated with the go_rna of many other GO terms, with 1,161 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible PRSS42P-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Negative regulation of myoblast fusion, and Protein K48-linked ubiquitination. Each is linked with PRSS42P in more than 5 cancer types. Because this analysis shows association rather than direction, both PRSS42P-to-partner and partner-to-PRSS42P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by PRSS42P-low versus PRSS42P-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS42P→partner) and Y-score (partner→PRSS42P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.087	+0.072	<.001	.009	3	6
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.074	+0.063	.006	.004	3	6
LUNG_NSCLC_LUSC	Protein K48-linked ubiquitination →	+0.038	+0.037	.005	.006	3	5
LARGE_INTESTINE	Positive regulation of CD8-positive, alpha-beta T cell differentiation →	+0.173	+0.024	<.001	.002	2	6
BREAST	Regulation of mRNA processing →	+0.055	+0.082	.003	.008	2	6
SOFT_TISSUE	mRNA destabilization →	+0.037	+0.032	.009	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,161 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by PRSS42P expression — BREAST

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