PRSS3P3

Across TCGA pan-cancer cohorts, PRSS3P3 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated PRSS3P3 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PRSS3P3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PRSS3P3 expression acts as an unfavorable survival marker, although some lineages such as SKCM and CESC show a favorable association.

UCEC, SKCM, and READ are the cancer types where PRSS3P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.740	0.845	.023	36	view →
SKCM	OS	Tertile	All	0.555	0.313	.001	33	view →
READ	OS	Tertile	II,III,IV	0.585	0.926	.009	30	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
CESC	OS	Tertile	All	0.977	0.853	.028	18	view →
THYM	OS	Tertile	II,III,IV	1.000	0.663	.003	13	view →
MESO	OS	Tertile	IV	0.384	0.634	.023	9	view →
KIRC	DFS	Tertile	III,IV	0.859	0.677	.033	8	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

PRSS3P3–UCEC (DFS)

Open the UCEC breakdown →