PRSS33

Across TCGA patient cohorts, PRSS33 protein abundance is significantly associated with the RNA expression of many other genes, with 14,445 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRSS33-associated genes across cancer lineages are RBBP8, SRPX, and LPCAT3. Each is linked with PRSS33 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRSS33-to-partner and partner-to-PRSS33 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRSS33 versus RBBP8 in OV, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS33→partner) and Y-score (partner→PRSS33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RBBP8 →	+1.159	+1.234	<.001	.001	3	1
OV	SRPX →	-1.137	-1.467	.004	.007	3	1
OV	LPCAT3 →	+1.558	+2.088	.001	.002	3	1
OV	SUDS3 →	+0.804	+1.638	.001	.003	3	1
OV	SERPINI2 →	-1.469	-1.187	<.001	.003	3	1
OV	CD2 →	-2.280	-1.577	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,445 associations by consensus.

PRSS33 vs RBBP8 — OV

Explore this scatter interactively →