PRSS33

Across TCGA cell cohorts, PRSS33 RNA expression is significantly associated with the go_rna of many other GO terms, with 894 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible PRSS33-associated GO terms across cancer lineages are Keratan sulfate proteoglycan metabolic process, GDF15-GFRAL signaling pathway, and Regulation of epithelial cell apoptotic process. Each is linked with PRSS33 in more than 4 cancer types. Because this analysis shows association rather than direction, both PRSS33-to-partner and partner-to-PRSS33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Keratan sulfate proteoglycan metabolic process grouped by PRSS33-low versus PRSS33-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS33→partner) and Y-score (partner→PRSS33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Keratan sulfate proteoglycan metabolic process →	+0.057	+1.007	.003	.003	3	5
STOMACH	GDF15-GFRAL signaling pathway →	+0.964	+0.629	.003	.002	3	5
PANCREAS	Regulation of epithelial cell apoptotic process →	+0.110	+1.067	.002	.002	3	4
PANCREAS	Negative regulation of epithelial cell apoptotic process →	+0.122	+0.807	.002	.005	3	4
PANCREAS	Regulation of low-density lipoprotein particle receptor catabolic process →	+0.084	+0.855	.002	.003	3	4
PANCREAS	Negative regulation of protein transport →	+0.043	+0.821	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 894 associations by consensus.

Keratan sulfate proteoglycan metabolic process by PRSS33 expression — SKIN

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