PRSS33

Across TCGA cell cohorts, PRSS33 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PRSS33-associated genes across cancer lineages are C4orf50 and ZNF705G. Each is linked with PRSS33 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRSS33-to-partner and partner-to-PRSS33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C4orf50 grouped by PRSS33-low versus PRSS33-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS33→partner) and Y-score (partner→PRSS33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	C4orf50 →	+0.020	+4.684	<.001	.002	3	1
SKIN	ZNF705G →	+0.027	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

C4orf50 by PRSS33 expression — SKIN

Explore this box plot interactively →