PRSS23

Across TCGA patient cohorts, PRSS23 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,715 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRSS23-associated proteins across cancer lineages are DAPK3, LUZP1, and SMOC2. Each is linked with PRSS23 in more than 8 cancer types. Because this analysis shows association rather than direction, both PRSS23-to-partner and partner-to-PRSS23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRSS23 versus DAPK3 in UCEC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS23→partner) and Y-score (partner→PRSS23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DAPK3 →	+0.530	+0.733	<.001	.001	3	9
OV	LUZP1 →	+0.355	+0.937	<.001	<.001	3	8
CCRCC	SMOC2 →	+1.213	+0.766	<.001	<.001	3	8
GBM	SPARC →	+0.643	+1.120	<.001	<.001	3	8
GBM	CAVIN3 →	+0.668	+0.984	<.001	<.001	3	8
CCRCC	TGFBI →	+0.850	+0.725	<.001	.004	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,715 associations by consensus.

PRSS23 vs DAPK3 — UCEC

Explore this scatter interactively →