PRSS23

Across TCGA patient cohorts, PRSS23 protein abundance is significantly associated with the RNA expression of many other genes, with 11,743 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRSS23-associated genes across cancer lineages are FN1, OR7E2P, and MYL9. Each is linked with PRSS23 in more than 7 cancer types. Because this analysis shows association rather than direction, both PRSS23-to-partner and partner-to-PRSS23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRSS23 versus FN1 in COAD, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS23→partner) and Y-score (partner→PRSS23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FN1 →	+1.663	+0.535	.003	.001	2	8
UCEC	OR7E2P →	+1.147	+0.658	<.001	<.001	3	7
GBM	MYL9 →	+1.214	+0.618	<.001	<.001	3	6
OV	LAMA4 →	+0.755	+0.538	<.001	.005	3	6
OV	IGSF21 →	+0.700	+0.679	.005	.006	3	6
GBM	COL5A1 →	+1.781	+0.712	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,743 associations by consensus.

PRSS23 vs FN1 — COAD

Explore this scatter interactively →