PRSS23

Across TCGA cell cohorts, PRSS23 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,328 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PRSS23-associated GO terms across cancer lineages are Integrin-mediated signaling pathway, Biological process involved in symbiotic interaction, and Cellular response to environmental stimulus. Each is linked with PRSS23 in more than 15 cancer types. Because this analysis shows association rather than direction, both PRSS23-to-partner and partner-to-PRSS23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Integrin-mediated signaling pathway grouped by PRSS23-low versus PRSS23-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS23→partner) and Y-score (partner→PRSS23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Integrin-mediated signaling pathway →	+0.193	+3.803	<.001	<.001	3	16
BONE	Biological process involved in symbiotic interaction →	+0.118	+5.621	<.001	<.001	3	14
SOFT_TISSUE	Cellular response to environmental stimulus →	+0.041	+2.622	<.001	<.001	3	14
BONE	Maintenance of protein location in cell →	+0.149	+4.638	<.001	<.001	3	14
STOMACH	Wound healing →	+0.112	+3.508	<.001	<.001	3	14
BONE	Maintenance of protein location →	+0.155	+5.233	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,328 associations by consensus.

Integrin-mediated signaling pathway by PRSS23 expression — BONE

Explore this box plot interactively →