PRSS16

Across TCGA patient cohorts, PRSS16 protein abundance is significantly associated with the RNA expression of many other genes, with 574 significant associations in total. COAD shows the largest number of these associations.

The most reproducible PRSS16-associated genes across cancer lineages are USP30-AS1, TTYH2, and OR51C1P. Each is linked with PRSS16 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRSS16-to-partner and partner-to-PRSS16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRSS16 versus USP30-AS1 in COAD, with a Pearson correlation of -0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS16→partner) and Y-score (partner→PRSS16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	USP30-AS1 →	-1.382	-0.564	<.001	.002	3	2
LSCC	TTYH2 →	+1.274	+0.761	.005	.008	3	1
LSCC	OR51C1P →	+0.240	+0.793	<.001	.003	3	1
LSCC	MIR199B →	+1.100	+0.743	.004	.004	3	1
LSCC	RNA5SP41 →	+1.170	+0.829	.004	.007	3	1
LSCC	AURKBP1 →	+0.120	+0.743	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 574 associations by consensus.

PRSS16 vs USP30-AS1 — COAD

Explore this scatter interactively →