PRSS16

Across TCGA cell cohorts, PRSS16 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,941 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PRSS16-associated GO terms across cancer lineages are Bundle of His cell-Purkinje myocyte adhesion involved in cell communication, Establishment of epithelial cell apical/basal polarity, and Response to indole-3-methanol. Each is linked with PRSS16 in more than 11 cancer types. Because this analysis shows association rather than direction, both PRSS16-to-partner and partner-to-PRSS16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bundle of His cell-Purkinje myocyte adhesion involved in cell communication grouped by PRSS16-low versus PRSS16-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS16→partner) and Y-score (partner→PRSS16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Bundle of His cell-Purkinje myocyte adhesion involved in cell communication →	+0.643	+1.066	.008	.005	3	12
LUNG_NSCLC_LUSC	Establishment of epithelial cell apical/basal polarity →	-0.231	-1.615	.001	.002	3	11
LUNG_NSCLC_LUSC	Response to indole-3-methanol →	+0.255	+2.042	<.001	<.001	3	11
LUNG_SCLC	Negative regulation of Arp2/3 complex-mediated actin nucleation →	+0.196	+2.336	.003	<.001	3	11
BONE	Regulation of myoblast fusion →	+0.084	+1.550	.003	<.001	3	10
STOMACH	Response to molecule of fungal origin →	+1.681	+2.503	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,941 associations by consensus.

Bundle of His cell-Purkinje myocyte adhesion involved in cell communication by PRSS16 expression — SOFT_TISSUE

Explore this box plot interactively →