Across TCGA cell cohorts, PRSS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 896 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible PRSS1-associated GO terms across cancer lineages are Regulation of tolerance induction dependent upon immune response, Regulation of toll-like receptor 2 signaling pathway, and Viral budding via host ESCRT complex. Each is linked with PRSS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PRSS1-to-partner and partner-to-PRSS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS1→partner) and Y-score (partner→PRSS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Regulation of tolerance induction dependent upon immune response →	+0.648	+0.038	.002	.005	2	7
PANCREAS	Regulation of toll-like receptor 2 signaling pathway →	+0.096	+2.296	.001	.009	3	5
PANCREAS	Viral budding via host ESCRT complex →	+0.088	+2.427	<.001	.004	3	5
PANCREAS	'de novo' GDP-L-fucose biosynthetic process →	+0.171	+3.430	<.001	<.001	3	5
PANCREAS	Ephrin receptor signaling pathway →	+0.100	+3.282	.001	.001	3	5
PANCREAS	Lateral line system development →	+1.578	+2.666	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 896 associations by consensus.

Exploration

PRSS1 survival (RNA) · tumor vs normal (RNA) · all PRSS1 data types