Across TCGA cell cohorts, PRRT4 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRRT4-associated genes across cancer lineages are PRKACG, KCNG4, and SRARP. Each is linked with PRRT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRRT4-to-partner and partner-to-PRRT4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRRT4→partner) and Y-score (partner→PRRT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	PRKACG →	+0.035	+4.044	<.001	.009	3	1
BLOOD_Leukemia	KCNG4 →	+0.004	+4.539	.009	.007	3	1
BLOOD_Leukemia	SRARP →	+0.006	+4.276	<.001	.007	3	1
BLOOD_Leukemia	LYPD2 →	+0.071	+4.152	<.001	.009	3	1
OVARY	SLC39A12 →	+0.006	+4.700	.006	.002	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

PRRT4 survival (RNA) · tumor vs normal (RNA) · all PRRT4 data types