PRRT3

Across TCGA patient cohorts, PRRT3 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,909 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PRRT3-associated proteins across cancer lineages are PDIA4, ASCC3, and WDR48. Each is linked with PRRT3 in more than 5 cancer types. Because this analysis shows association rather than direction, both PRRT3-to-partner and partner-to-PRRT3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRRT3 versus PDIA4 in LUAD, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRRT3→partner) and Y-score (partner→PRRT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PDIA4 →	-0.398	-0.521	<.001	.001	3	6
HNSC	ASCC3 →	-0.295	-0.645	<.001	<.001	3	5
HNSC	WDR48 →	+0.229	+0.614	<.001	<.001	3	5
BRCA	SND1 →	-0.248	-0.692	<.001	<.001	3	5
BRCA	EPM2AIP1 →	+0.403	+0.729	<.001	<.001	3	5
BRCA	PPIB →	-0.310	-0.798	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,909 associations by consensus.

PRRT3 vs PDIA4 — LUAD

Explore this scatter interactively →