PRRT3-AS1

Across TCGA pan-cancer cohorts, PRRT3-AS1 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated PRRT3-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher PRRT3-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated PRRT3-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and UCS show a favorable association.

UVM, LIHC, and UCEC are the cancer types where PRRT3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.770	0.414	<.001	85	view →
LIHC	OS	Tertile	All	0.673	0.844	<.001	80	view →
UCEC	DFS	Quartile	All	0.744	0.892	<.001	66	view →
SKCM	DFS	Median	All	0.674	0.800	<.001	53	view →
KIRP	OS	Tertile	II,III,IV	0.517	0.845	.003	53	view →
LGG	DFS	Median	All	0.637	0.830	<.001	52	view →
MESO	OS	Quartile	All	0.243	0.804	.006	40	view →
PAAD	DFS	Quartile	All	0.363	0.585	.003	26	view →
COAD	OS	Median	III,IV	0.390	0.759	.014	21	view →
SARC	DFS	Quartile	All	0.367	0.578	.005	21	view →
BLCA	OS	Median	III,IV	0.156	0.420	.010	17	view →
ACC	DFS	Median	III,IV	0.168	0.525	.010	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

PRRT3-AS1–UVM (DFS)

Open the UVM breakdown →