PRRT3-AS1

Across TCGA pan-cancer cohorts, PRRT3-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of PRRT3-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where PRRT3-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types PRRT3-AS1 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

KICH, COAD, and LIHC are the cancer types where PRRT3-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PRRT3-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	−1.213	<.001	10	view →
COAD	Female	All	+1.289	<.001	9	view →
LIHC	Female	II,III,IV	+1.276	<.001	8	view →
LUAD	Male	II,III,IV	+1.223	<.001	8	view →
LUSC	Male	All	+0.921	<.001	7	view →
BRCA	All	III,IV	−0.960	<.001	6	view →
STAD	All	All	+0.666	<.001	6	view →
KIRC	All	All	+0.314	<.001	6	view →
THCA	All	All	−0.356	<.001	5	view →
CHOL	All	All	+0.751	.015	4	view →
PRAD	All	All	+0.918	<.001	2	view →
BLCA	Male	IV	−1.244	.013	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

PRRT3-AS1–KICH

Open the KICH breakdown →