PRRG4

Across TCGA cell cohorts, PRRG4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,747 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PRRG4-associated GO terms across cancer lineages are Response to indole-3-methanol, Cellular response to indole-3-methanol, and Response to molecule of fungal origin. Each is linked with PRRG4 in more than 11 cancer types. Because this analysis shows association rather than direction, both PRRG4-to-partner and partner-to-PRRG4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to indole-3-methanol grouped by PRRG4-low versus PRRG4-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRRG4→partner) and Y-score (partner→PRRG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Response to indole-3-methanol →	+0.238	+1.886	<.001	<.001	3	12
PANCREAS	Cellular response to indole-3-methanol →	+0.209	+1.874	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Response to molecule of fungal origin →	+1.786	+1.898	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Cellular response to molecule of fungal origin →	+1.786	+1.898	<.001	<.001	3	11
URINARY_TRACT	Basolateral protein secretion →	+0.180	+1.492	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Serotonin secretion →	+1.686	+1.872	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,747 associations by consensus.

Response to indole-3-methanol by PRRG4 expression — URINARY_TRACT

Explore this box plot interactively →