PRRC1

Across TCGA patient cohorts, PRRC1 mutation is significantly associated with the RNA expression of many other genes, with 2,920 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRRC1-associated genes across cancer lineages are RNU6-1305P, MIR8082, and SEPTIN14P19. Each is linked with PRRC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PRRC1-to-partner and partner-to-PRRC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1305P grouped by PRRC1-low versus PRRC1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRRC1→partner) and Y-score (partner→PRRC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-1305P →	+0.300	+4.224	<.001	.002	3	3
UCEC	MIR8082 →	+0.324	+1.898	<.001	.009	3	2
BLCA	SEPTIN14P19 →	+0.053	+4.685	<.001	.007	3	2
COAD	RN7SL98P →	+0.208	+5.278	.001	<.001	3	2
UCEC	ZNF114-AS1 →	+0.370	+1.877	<.001	.001	3	2
SKCM	CYP4F27P →	+0.209	+3.408	.003	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,920 associations by consensus.

RNU6-1305P by PRRC1 expression — SKCM

Explore this box plot interactively →