PRR7

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PRR7 protein abundance is significantly associated with the RNA expression of many other genes, with 1,227 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRR7-associated genes across cancer lineages are LRP5L, VAC14, and TRIM14. Each is linked with PRR7 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR7-to-partner and partner-to-PRR7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRR7 versus LRP5L in GBM, with a Pearson correlation of -0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR7→partner) and Y-score (partner→PRR7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMLRP5L →-0.567-0.629.005.00431
GBMVAC14 →-0.427-0.800.002.00331
GBMTRIM14 →-0.927-0.814.007.00931
GBMNAGLU →-0.513-0.636.001.00431
GBMRHAG →+0.099+0.934.005.00231
GBMFHL5 →+1.229+0.768<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,227 associations by consensus.

PRR7 vs LRP5L — GBM

Per-sample scatter of PRR7 vs LRP5L in GBM (Pearson r = -0.48).

Explore this scatter interactively →

Exploration