PRR7

Across TCGA patient cohorts, PRR7 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible PRR7-associated genes across cancer lineages are RNU6-284P, OR51P1P, and SMIM34A. Each is linked with PRR7 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR7-to-partner and partner-to-PRR7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-284P grouped by PRR7-low versus PRR7-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR7→partner) and Y-score (partner→PRR7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-284P →	+0.368	+7.640	<.001	.009	3	1
BLCA	OR51P1P →	+0.054	+7.640	<.001	.009	3	1
BLCA	SMIM34A →	+0.049	+7.640	<.001	.009	3	1
BLCA	RNU6-256P →	+0.398	+7.640	<.001	.009	3	1
BLCA	TUBB4BP4 →	+0.153	+7.640	<.001	.009	3	1
BLCA	SPATA31A5 →	+0.009	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

RNU6-284P by PRR7 expression — BLCA

Explore this box plot interactively →