PRR7-AS1

Across TCGA pan-cancer cohorts, PRR7-AS1 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of PRR7-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where PRR7-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PRR7-AS1 is over-expressed in tumor, although a few such as BRCA and KICH show the opposite, repressed pattern.

COAD, KIRC, and KIRP are the cancer types where PRR7-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PRR7-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	III,IV	+1.299	<.001	12	view →
KIRC	Female	All	+0.422	<.001	12	view →
KIRP	Male	II,III,IV	+0.550	<.001	11	view →
LIHC	Male	II,III,IV	+0.318	<.001	8	view →
UCEC	All	II,III,IV	+0.773	<.001	6	view →
STAD	All	II,III,IV	+0.649	<.001	6	view →
READ	All	All	+0.757	.004	5	view →
LUAD	All	All	+0.314	<.001	5	view →
ESCA	Male	All	+0.826	.021	4	view →
CHOL	Male	All	+1.056	<.001	3	view →
BLCA	All	All	+0.334	.009	3	view →
BRCA	All	III,IV	−0.190	.031	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

PRR7-AS1–COAD

Open the COAD breakdown →